| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Neuroepithelial cell-transforming gene 1 protein (230-310 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NET1 |
| Gene ID: | 10276 |
| Uniprot ID: | ARHG8_HUMAN |
| Immunogen Region: | 230-310 aa |
| Specificity: | ARHG8 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 230-310 |
| Function | Acts as a guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death. |
| Protein Name | Neuroepithelial Cell-Transforming Gene 1 ProteinProto-Oncogene P65 Net1Rho Guanine Nucleotide Exchange Factor 8 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-8980692Reactome: R-HSA-9013026 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Neuroepithelial Cell-Transforming Gene 1 Protein antibodyAnti-Proto-Oncogene P65 Net1 antibodyAnti-Rho Guanine Nucleotide Exchange Factor 8 antibodyAnti-NET1 antibodyAnti-ARHGEF8 antibody |
Information sourced from Uniprot.org
