Anti-NET1 antibody (230-310 aa) (STJ191063)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 230-310
General Information
| Short Description | Rabbit polyclonal anti-Neuroepithelial cell-transforming gene 1 protein (230-310 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NET1 |
| Gene ID | 10276 |
| Uniprot ID | ARHG8_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 230-310 |
| Immunogen Region | 230-310 aa |
| Specificity | ARHG8 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Acts as a guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death. |
| Protein Name | Neuroepithelial Cell-Transforming Gene 1 ProteinProto-Oncogene P65 Net1Rho Guanine Nucleotide Exchange Factor 8 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-8980692Reactome: R-HSA-9013026 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Neuroepithelial Cell-Transforming Gene 1 Protein antibodyAnti-Proto-Oncogene P65 Net1 antibodyAnti-Rho Guanine Nucleotide Exchange Factor 8 antibodyAnti-NET1 antibodyAnti-ARHGEF8 antibody |
Information sourced from Uniprot.org