| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Serine/threonine-protein kinase Nek11 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NEK11 |
| Gene ID: |
79858 |
| Uniprot ID: |
NEK11_HUMAN |
| Specificity: |
This antibody detects endogenous levels of NEK11 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human NEK11 |
| Post Translational Modifications | Phosphorylated by NEK2. Phosphorylation at Ser-273 is important for its activation. |
| Function | Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation. |
| Protein Name | Serine/Threonine-Protein Kinase Nek11Never In Mitosis A-Related Kinase 11Nima-Related Protein Kinase 11 |
| Cellular Localisation | NucleusNucleolusNuclear During Interphase But Moves To The Polar Microtubules During Prometaphase And MetaphaseAccumulates In The Nucleolus In G1/S-Arrested Cells |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase Nek11 antibodyAnti-Never In Mitosis A-Related Kinase 11 antibodyAnti-Nima-Related Protein Kinase 11 antibodyAnti-NEK11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
