| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Serine/Threonine-Protein Kinase Nek11 is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification: |
Affinity purification |
| Concentration: |
0.4 mg/mL |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Tissue Specificity | Poorly expressed in cerebellum, trachea, lung, appendix, and uterus. |
| Post Translational Modifications | Phosphorylated by NEK2. Phosphorylation at Ser-273 is important for its activation. |
| Function | Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation. |
| Protein Name | Serine/Threonine-Protein Kinase Nek11Never In Mitosis A-Related Kinase 11Nima-Related Protein Kinase 11 |
| Cellular Localisation | NucleusNucleolusNuclear During Interphase But Moves To The Polar Microtubules During Prometaphase And MetaphaseAccumulates In The Nucleolus In G1/S-Arrested Cells |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase Nek11 antibodyAnti-Never In Mitosis A-Related Kinase 11 antibodyAnti-Nima-Related Protein Kinase 11 antibodyAnti-NEK11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
