Anti-NEK11 antibody (STJA0004615)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human NEK11
General Information
| Short Description | Rabbit polyclonal anti-Serine/Threonine-Protein Kinase Nek11 for use in WB and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.4 mg/mL |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000 |
| Formulation | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | NEK11 |
| Gene ID | 79858 |
| Uniprot ID | NEK11_HUMAN |
| Immunogen | Recombinant protein of human NEK11 |
Additional Info
| Tissue Specificity | Poorly expressed in cerebellum, trachea, lung, appendix, and uterus. |
| Post Translational Modifications | Phosphorylated by NEK2. Phosphorylation at Ser-273 is important for its activation. |
| Function | Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation. |
| Protein Name | Serine/Threonine-Protein Kinase Nek11Never In Mitosis A-Related Kinase 11Nima-Related Protein Kinase 11 |
| Database Links | |
| Cellular Localisation | NucleusNucleolusNuclear During Interphase But Moves To The Polar Microtubules During Prometaphase And MetaphaseAccumulates In The Nucleolus In G1/S-Arrested Cells |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase Nek11 antibodyAnti-Never In Mitosis A-Related Kinase 11 antibodyAnti-Nima-Related Protein Kinase 11 antibodyAnti-NEK11 antibody |
Information sourced from Uniprot.org