Anti-NDUFB10 antibody (1-172) (STJ26523)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NDUFB10 (1-172) antibody for use in WB, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NDUFB10 |
| Gene ID | 4716 |
| Uniprot ID | NDUBA_HUMAN |
| Immunogen Region | 1-172 |
| Immunogen Sequence | MPDSWDKDVYPEPPRRTPVQ PNPIVYMMKAFDLIVDRPVT LVREFIERQHAKNRYYYYHR QYRRVPDITECKEEDIMCMY EAEMQWKRDYKVDQEIINIM QDRLKACQQREGQNYQQNCI KEVEQFTQVAKAYQDRYQDL GAYSSARKCLAKQRQRMLQE RKAAKEAAAATS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human NDUFB10 (NP_004539.1). |
Additional Info
| Post Translational Modifications | The formation of intramolecular disulfide bonds is assisted by CHCHD4 and ensures folding, import into the mitochondrion and is required for the function in mitochondrial respiratory chain complex I assembly. |
| Function | Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain. |
| Protein Name | Nadh Dehydrogenase Ubiquinone 1 Beta Subcomplex Subunit 10Complex I-PdswCi-PdswNadh-Ubiquinone Oxidoreductase Pdsw Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-6799198 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone 1 Beta Subcomplex Subunit 10 antibodyAnti-Complex I-Pdsw antibodyAnti-Ci-Pdsw antibodyAnti-Nadh-Ubiquinone Oxidoreductase Pdsw Subunit antibodyAnti-NDUFB10 antibody |
Information sourced from Uniprot.org