| Host: | Rabbit |
| Applications: | WB/IP/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NDUFB10 |
| Gene ID: | 4716 |
| Uniprot ID: | NDUBA_HUMAN |
| Immunogen Region: | 1-172 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human NDUFB10 (NP_004539.1). |
| Immunogen Sequence: | MPDSWDKDVYPEPPRRTPVQ PNPIVYMMKAFDLIVDRPVT LVREFIERQHAKNRYYYYHR QYRRVPDITECKEEDIMCMY EAEMQWKRDYKVDQEIINIM QDRLKACQQREGQNYQQNCI KEVEQFTQVAKAYQDRYQDL GAYSSARKCLAKQRQRMLQE RKAAKEAAAATS |
| Post Translational Modifications | The formation of intramolecular disulfide bonds is assisted by CHCHD4 and ensures folding, import into the mitochondrion and is required for the function in mitochondrial respiratory chain complex I assembly. |
| Function | Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain. |
| Protein Name | Nadh Dehydrogenase Ubiquinone 1 Beta Subcomplex Subunit 10Complex I-PdswCi-PdswNadh-Ubiquinone Oxidoreductase Pdsw Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-6799198 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone 1 Beta Subcomplex Subunit 10 antibodyAnti-Complex I-Pdsw antibodyAnti-Ci-Pdsw antibodyAnti-Nadh-Ubiquinone Oxidoreductase Pdsw Subunit antibodyAnti-NDUFB10 antibody |
Information sourced from Uniprot.org