Anti-NDOR1 antibody (STJA0007193)

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STJA0007193
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-NADPH-dependent diflavin oxidoreductase 1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:NDOR1
Gene ID:27158
Uniprot ID:NDOR1_HUMAN
Immunogen:Synthesized peptide derived from human NDOR1/NR1
Specificity:This antibody detects endogenous levels of NDOR1/NR1 at Human, Mouse
Function NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the 2Fe-2S cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the 2Fe-2S cluster of CISD1 and activate this protein implicated in Fe/S cluster repair. In vitro can fully activate methionine synthase/MTR in the presence of soluble cytochrome b5/CYB5A.
Protein Name Nadph-Dependent Diflavin Oxidoreductase 1
Nadph-Dependent Fmn And Fad-Containing Oxidoreductase
Novel Reductase 1
Database Links Reactome: R-HSA-2564830
Cellular Localisation Cytoplasm
Perinuclear Region
Concentrated In Perinuclear Structure
Alternative Antibody Names Anti-Nadph-Dependent Diflavin Oxidoreductase 1 antibody
Anti-Nadph-Dependent Fmn And Fad-Containing Oxidoreductase antibody
Anti-Novel Reductase 1 antibody
Anti-NDOR1 antibody
Anti-NR1 antibody

Information sourced from Uniprot.org

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