Anti-NDOR1 antibody (STJA0007193)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human NDOR1/NR1
General Information
| Short Description | Rabbit polyclonal anti-NADPH-dependent diflavin oxidoreductase 1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NDOR1 |
| Gene ID | 27158 |
| Uniprot ID | NDOR1_HUMAN |
| Immunogen | Synthesized peptide derived from human NDOR1/NR1 |
| Specificity | This antibody detects endogenous levels of NDOR1/NR1 at Human, Mouse |
Additional Info
| Function | NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the 2Fe-2S cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the 2Fe-2S cluster of CISD1 and activate this protein implicated in Fe/S cluster repair. In vitro can fully activate methionine synthase/MTR in the presence of soluble cytochrome b5/CYB5A. |
| Protein Name | Nadph-Dependent Diflavin Oxidoreductase 1Nadph-Dependent Fmn And Fad-Containing OxidoreductaseNovel Reductase 1 |
| Database Links | Reactome: R-HSA-2564830 |
| Cellular Localisation | CytoplasmPerinuclear RegionConcentrated In Perinuclear Structure |
| Alternative Antibody Names | Anti-Nadph-Dependent Diflavin Oxidoreductase 1 antibodyAnti-Nadph-Dependent Fmn And Fad-Containing Oxidoreductase antibodyAnti-Novel Reductase 1 antibodyAnti-NDOR1 antibodyAnti-NR1 antibody |
Information sourced from Uniprot.org