• Western blot analysis of Daudi, using NCR3 Rabbit polyclonal antibody (STJ29233) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-NCR3 antibody (19-201) (STJ29233)

SKU:
STJ29233

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NCR3 (19-201) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NCR3
Gene ID: 259197
Uniprot ID: NCTR3_HUMAN
Immunogen Region: 19-201
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-201 of human NCR3 (NP_667341.1).
Immunogen Sequence: LWVSQPPEIRTLEGSSAFLP CSFNASQGRLAIGSVTWFRD EVVPGKEVRNGTPEFRGRLA PLASSRFLHDHQAELHIRDV RGHDASIYVCRVEVLGLGVG TGNGTRLVVEKEHPQLG
Tissue Specificity Selectively expressed by all resting and activated NK cells and weakly expressed in spleen.
Function Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
Protein Name Natural Cytotoxicity Triggering Receptor 3
Activating Natural Killer Receptor P30
Natural Killer Cell P30-Related Protein
Nk-P30
Nkp30
Cd Antigen Cd337
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Natural Cytotoxicity Triggering Receptor 3 antibody
Anti-Activating Natural Killer Receptor P30 antibody
Anti-Natural Killer Cell P30-Related Protein antibody
Anti-Nk-P30 antibody
Anti-Nkp30 antibody
Anti-Cd Antigen Cd337 antibody
Anti-NCR3 antibody
Anti-1C7 antibody
Anti-LY117 antibody

Information sourced from Uniprot.org

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