| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NCR1 |
| Gene ID: | 9437 |
| Uniprot ID: | NCTR1_HUMAN |
| Immunogen Region: | 22-254 |
| Immunogen Sequence: | QQQTLPKPFIWAEPHFMVPK EKQVTICCQGNYGAVEYQLH FEGSLFAVDRPKPPERINKV QFYIPDMNSRMAGQYSCIYR VGELWSEPSNLLDLVVTEMY DTPTLSVHPGPEVISGEKVT FYCRLDTATSMFLLLKEGRS SHVQRGYGKVQAEFPLGPVT TAHRGTYRCFGSYNNHAWSF PSEPVKLLVTGDIENTSLAP EDPTFPADTWGTYLLTTETG LQKDHALWDHTAQ |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-254 of human NCR1 (NP_004820.2). |
| Tissue Specificity | Selectively expressed by both resting and activated NK cells. |
| Post Translational Modifications | N-glycosylated. O-glycosylated. |
| Function | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| Protein Name | Natural Cytotoxicity Triggering Receptor 1Lymphocyte Antigen 94 HomologNk Cell-Activating ReceptorNatural Killer Cell P46-Related ProteinNk-P46Nkp46Hnkp46Cd Antigen Cd335 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Natural Cytotoxicity Triggering Receptor 1 antibodyAnti-Lymphocyte Antigen 94 Homolog antibodyAnti-Nk Cell-Activating Receptor antibodyAnti-Natural Killer Cell P46-Related Protein antibodyAnti-Nk-P46 antibodyAnti-Nkp46 antibodyAnti-Hnkp46 antibodyAnti-Cd Antigen Cd335 antibodyAnti-NCR1 antibodyAnti-LY94 antibody |
Information sourced from Uniprot.org
