Anti-NCR1 antibody (22-254) (STJ11105718)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Natural Cytotoxicity Triggering Receptor 1 (22-254) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NCR1 |
| Gene ID | 9437 |
| Uniprot ID | NCTR1_HUMAN |
| Immunogen Region | 22-254 |
| Immunogen Sequence | QQQTLPKPFIWAEPHFMVPK EKQVTICCQGNYGAVEYQLH FEGSLFAVDRPKPPERINKV QFYIPDMNSRMAGQYSCIYR VGELWSEPSNLLDLVVTEMY DTPTLSVHPGPEVISGEKVT FYCRLDTATSMFLLLKEGRS SHVQRGYGKVQAEFPLGPVT TAHRGTYRCFGSYNNHAWSF PSEPVKLLVTGDIENTSLAP EDPTFPADTWGTYLLTTETG LQKDHALWDHTAQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 22-254 of human NCR1 (NP_004820.2). |
Additional Info
| Tissue Specificity | Selectively expressed by both resting and activated NK cells. |
| Post Translational Modifications | N-glycosylated. O-glycosylated. |
| Function | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| Protein Name | Natural Cytotoxicity Triggering Receptor 1Lymphocyte Antigen 94 HomologNk Cell-Activating ReceptorNatural Killer Cell P46-Related ProteinNk-P46Nkp46Hnkp46Cd Antigen Cd335 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Natural Cytotoxicity Triggering Receptor 1 antibodyAnti-Lymphocyte Antigen 94 Homolog antibodyAnti-Nk Cell-Activating Receptor antibodyAnti-Natural Killer Cell P46-Related Protein antibodyAnti-Nk-P46 antibodyAnti-Nkp46 antibodyAnti-Hnkp46 antibodyAnti-Cd Antigen Cd335 antibodyAnti-NCR1 antibodyAnti-LY94 antibody |
Information sourced from Uniprot.org