Anti-NABP1 antibody (STJA0004643)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFusion protein of human NABP1
General Information
| Short Description | Rabbit polyclonal anti-Soss Complex Subunit B2 for use in IHC and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1.38 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:50-1:200 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | NABP1 |
| Gene ID | 64859 |
| Uniprot ID | SOSB2_HUMAN |
| Immunogen | Fusion protein of human NABP1 |
Additional Info
| Function | Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. |
| Protein Name | Soss Complex Subunit B2Nucleic Acid-Binding Protein 1Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 2aSensor Of Single-Strand Dna Complex Subunit B2Sensor Of Ssdna Subunit B2Soss-B2Single-Stranded Dna-Binding Protein 2Hssb2 |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | NucleusLocalizes To Nuclear Foci Following Dna Damage |
| Alternative Antibody Names | Anti-Soss Complex Subunit B2 antibodyAnti-Nucleic Acid-Binding Protein 1 antibodyAnti-Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 2a antibodyAnti-Sensor Of Single-Strand Dna Complex Subunit B2 antibodyAnti-Sensor Of Ssdna Subunit B2 antibodyAnti-Soss-B2 antibodyAnti-Single-Stranded Dna-Binding Protein 2 antibodyAnti-Hssb2 antibodyAnti-NABP1 antibodyAnti-OBFC2A antibodyAnti-SSB2 antibody |
Information sourced from Uniprot.org