Anti-MYOD1 antibody (100-200 aa) [ABT-MYOD1] (STJ196793)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human MyoD1 at the amino acid range 100-200
General Information
| Short Description | Mouse monoclonal anti-Myoblast determination protein 1 (100-200 aa) for use in WB, IHC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ABT-MYOD1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | IHC-P 1:100-500WB 1:100-2000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYOD1 |
| Gene ID | 4654 |
| Uniprot ID | MYOD1_HUMAN |
| Immunogen | Synthesized peptide derived from the human MyoD1 at the amino acid range 100-200 |
| Immunogen Region | 100-200 aa |
| Specificity | This antibody detects endogenous levels of human MyoD1. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section |
Additional Info
| Function | Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins. |
| Protein Name | Myoblast Determination Protein 1Class C Basic Helix-Loop-Helix Protein 1Bhlhc1Myogenic Factor 3Myf-3 |
| Database Links | Reactome: R-HSA-525793Reactome: R-HSA-9839394 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Myoblast Determination Protein 1 antibodyAnti-Class C Basic Helix-Loop-Helix Protein 1 antibodyAnti-Bhlhc1 antibodyAnti-Myogenic Factor 3 antibodyAnti-Myf-3 antibodyAnti-MYOD1 antibodyAnti-BHLHC1 antibodyAnti-MYF3 antibodyAnti-MYOD antibody |
Information sourced from Uniprot.org