Anti-MYL3 antibody (1-195) (STJ28745)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MYL3 (1-195) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYL3 |
| Gene ID | 4634 |
| Uniprot ID | MYL3_HUMAN |
| Immunogen Region | 1-195 |
| Immunogen Sequence | MAPKKPEPKKDDAKAAPKAA PAPAPPPEPERPKEVEFDAS KIKIEFTPEQIEEFKEAFML FDRTPKCEMKITYGQCGDVL RALGQNPTQAEVLRVLGKPR QEELNTKMMDFETFLPMLQH ISKNKDTGTYEDFVEGLRVF DKEGNGTVMGAELRHVLATL GERLTEDEVEKLMAGQEDSN GCINYEAFVKHIMSS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MYL3 (NP_000249.1). |
Additional Info
| Post Translational Modifications | The N-terminus is blocked. N-terminus is methylated by METTL11A/NTM1. |
| Function | Regulatory light chain of myosin. Does not bind calcium. |
| Protein Name | Myosin Light Chain 3Cardiac Myosin Light Chain 1Cmlc1Myosin Light Chain 1 - Slow-Twitch Muscle B/Ventricular IsoformMlc1sbVentricular Myosin Alkali Light ChainVentricular Myosin Light Chain 1VlclVentricular/Slow Twitch Myosin Alkali Light ChainMlc-Lv/Sb |
| Database Links | Reactome: R-HSA-390522 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Myosin Light Chain 3 antibodyAnti-Cardiac Myosin Light Chain 1 antibodyAnti-Cmlc1 antibodyAnti-Myosin Light Chain 1 - Slow-Twitch Muscle B/Ventricular Isoform antibodyAnti-Mlc1sb antibodyAnti-Ventricular Myosin Alkali Light Chain antibodyAnti-Ventricular Myosin Light Chain 1 antibodyAnti-Vlcl antibodyAnti-Ventricular/Slow Twitch Myosin Alkali Light Chain antibodyAnti-Mlc-Lv/Sb antibodyAnti-MYL3 antibody |
Information sourced from Uniprot.org