Anti-MYH10 antibody (STJA0007354)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MYH10
General Information
| Short Description | Rabbit polyclonal anti-Myosin-10 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYH10 |
| Gene ID | 4628 |
| Uniprot ID | MYH10_HUMAN |
| Immunogen | Synthesized peptide derived from human MYH10 |
| Specificity | This antibody detects endogenous levels of MYH10 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Phosphorylated by ABL2. |
| Function | Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension.this function is mechanically antagonized by MYH9. (Microbial infection) Acts as a receptor for herpes simplex virus 1/HHV-1 envelope glycoprotein B. |
| Protein Name | Myosin-10Cellular Myosin Heavy Chain - Type BMyosin Heavy Chain 10Myosin Heavy Chain - Non-Muscle IibNon-Muscle Myosin Heavy Chain BNmmhc-BNon-Muscle Myosin Heavy Chain IibNmmhc Ii-BNmmhc-Iib |
| Database Links | Reactome: R-HSA-3928663Reactome: R-HSA-416572Reactome: R-HSA-5625740Reactome: R-HSA-5625900Reactome: R-HSA-5627117Reactome: R-HSA-5627123 |
| Cellular Localisation | Cell ProjectionLamellipodiumColocalizes With Mcc At The Leading Edge Of Migrating CellsCell Membrane(Microbial Infection) Localizes At The Surface Of The Cell Membrane Following Infection By Herpes Simplex Virus 1/Hhv-1 |
| Alternative Antibody Names | Anti-Myosin-10 antibodyAnti-Cellular Myosin Heavy Chain - Type B antibodyAnti-Myosin Heavy Chain 10 antibodyAnti-Myosin Heavy Chain - Non-Muscle Iib antibodyAnti-Non-Muscle Myosin Heavy Chain B antibodyAnti-Nmmhc-B antibodyAnti-Non-Muscle Myosin Heavy Chain Iib antibodyAnti-Nmmhc Ii-B antibodyAnti-Nmmhc-Iib antibodyAnti-MYH10 antibody |
Information sourced from Uniprot.org