| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Myosin-10 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MYH10 |
| Gene ID: |
4628 |
| Uniprot ID: |
MYH10_HUMAN |
| Specificity: |
This antibody detects endogenous levels of MYH10 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human MYH10 |
| Post Translational Modifications | Phosphorylated by ABL2. |
| Function | Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension.this function is mechanically antagonized by MYH9. |
| Protein Name | Myosin-10Cellular Myosin Heavy Chain - Type BMyosin Heavy Chain 10Myosin Heavy Chain - Non-Muscle IibNon-Muscle Myosin Heavy Chain BNmmhc-BNon-Muscle Myosin Heavy Chain IibNmmhc Ii-BNmmhc-Iib |
| Database Links | Reactome: R-HSA-3928663Reactome: R-HSA-416572Reactome: R-HSA-5625740Reactome: R-HSA-5625900Reactome: R-HSA-5627117Reactome: R-HSA-5627123 |
| Cellular Localisation | Cell ProjectionLamellipodiumColocalizes With Mcc At The Leading Edge Of Migrating Cells |
| Alternative Antibody Names | Anti-Myosin-10 antibodyAnti-Cellular Myosin Heavy Chain - Type B antibodyAnti-Myosin Heavy Chain 10 antibodyAnti-Myosin Heavy Chain - Non-Muscle Iib antibodyAnti-Non-Muscle Myosin Heavy Chain B antibodyAnti-Nmmhc-B antibodyAnti-Non-Muscle Myosin Heavy Chain Iib antibodyAnti-Nmmhc Ii-B antibodyAnti-Nmmhc-Iib antibodyAnti-MYH10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
