| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MXI1 (170-295) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MXI1 |
| Gene ID: |
4601 |
| Uniprot ID: |
MXI1_HUMAN |
| Immunogen Region: |
170-295 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 170-295 of human MXI1 (NP_569157.2). |
| Immunogen Sequence: |
HTTLGLLNKAKAHIKKLEEA ERKSQHQLENLEREQRFLKW RLEQLQGPQEMERIRMDSIG STISSDRSDSEREEIEVDVE STEFSHGEVDNISTTSISDI DDHSSLPSIGSDEGYSSASV KLSFTS |
| Tissue Specificity | High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. |
| Function | Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CACGATG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX. |
| Protein Name | Max-Interacting Protein 1Max Interactor 1Class C Basic Helix-Loop-Helix Protein 11Bhlhc11 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Max-Interacting Protein 1 antibodyAnti-Max Interactor 1 antibodyAnti-Class C Basic Helix-Loop-Helix Protein 11 antibodyAnti-Bhlhc11 antibodyAnti-MXI1 antibodyAnti-BHLHC11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
