Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-MXI1 (170-295) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MXI1 |
Gene ID: |
4601 |
Uniprot ID: |
MXI1_HUMAN |
Immunogen Region: |
170-295 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 170-295 of human MXI1 (NP_569157.2). |
Immunogen Sequence: |
HTTLGLLNKAKAHIKKLEEA ERKSQHQLENLEREQRFLKW RLEQLQGPQEMERIRMDSIG STISSDRSDSEREEIEVDVE STEFSHGEVDNISTTSISDI DDHSSLPSIGSDEGYSSASV KLSFTS |
Tissue Specificity | High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. |
Function | Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CACGATG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX. |
Protein Name | Max-Interacting Protein 1Max Interactor 1Class C Basic Helix-Loop-Helix Protein 11Bhlhc11 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Max-Interacting Protein 1 antibodyAnti-Max Interactor 1 antibodyAnti-Class C Basic Helix-Loop-Helix Protein 11 antibodyAnti-Bhlhc11 antibodyAnti-MXI1 antibodyAnti-BHLHC11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance