| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MUT (451-750) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MMUT |
| Gene ID: |
4594 |
| Uniprot ID: |
MUTA_HUMAN |
| Immunogen Region: |
451-750 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 451-750 of human MUT (NP_000246.2). |
| Immunogen Sequence: |
EMGGMAKAVAEGIPKLRIEE CAARRQARIDSGSEVIVGVN KYQLEKEDAVEVLAIDNTSV RNRQIEKLKKIKSSRDQALA ERCLAALTECAASGDGNILA LAVDASRARCTVGEITDALK KVFGEHKANDRMVSGAYRQE FGESKEITSAIKRVHKFMER EGRRPRLLVAKMGQDGHDRG AKVIATGFADLGFDVDIGPL FQTPREVAQQAVDADVHAVG ISTLAAGHKTLVPELIKEL |
| Function | Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle. |
| Protein Name | Methylmalonyl-Coa Mutase - MitochondrialMcmMethylmalonyl-Coa Isomerase |
| Database Links | Reactome: R-HSA-3359475Reactome: R-HSA-3359478Reactome: R-HSA-71032Reactome: R-HSA-9759218 |
| Cellular Localisation | Mitochondrion MatrixMitochondrionCytoplasm |
| Alternative Antibody Names | Anti-Methylmalonyl-Coa Mutase - Mitochondrial antibodyAnti-Mcm antibodyAnti-Methylmalonyl-Coa Isomerase antibodyAnti-MMUT antibodyAnti-MUT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
