| Host: |
Mouse |
| Applications: |
IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-MUM1 is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
MRQ-8 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Dilution Range: |
IHC 1:100 – 1:500 |
| Storage Instruction: |
Store at 2-8°C upon receipt. |
| Tissue Specificity | Lymphoid cells. |
| Post Translational Modifications | Phosphorylation by ROCK2 regulates IL-17 and IL-21 production. |
| Function | Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes. |
| Protein Name | Interferon Regulatory Factor 4Irf-4Lymphocyte-Specific Interferon Regulatory FactorLsirfMultiple Myeloma Oncogene 1Nf-Em5 |
| Database Links | Reactome: R-HSA-6785807Reactome: R-HSA-877300Reactome: R-HSA-909733 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Interferon Regulatory Factor 4 antibodyAnti-Irf-4 antibodyAnti-Lymphocyte-Specific Interferon Regulatory Factor antibodyAnti-Lsirf antibodyAnti-Multiple Myeloma Oncogene 1 antibodyAnti-Nf-Em5 antibodyAnti-IRF4 antibodyAnti-MUM1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Anti-MUM1 antibody [MRQ-43] (STJ16100460)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/149177/346802/STJ16100460_1__50143.1681998906.jpg?c=1 "Anti-MUM1 antibody [MRQ-43] (STJ16100460)")
![Anti-PAX-8 antibody [MRQ-50] (STJ16100462)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/149179/346805/STJ16100462_1__32066.1681998909.jpg?c=1 "Anti-PAX-8 antibody [MRQ-50] (STJ16100462)")