Anti-MUC3 antibody [EBS-T-232] (STJ16101977)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenA BALB/c mouse was immunized with synthetic human MUC3 (SIB-35) peptide. Fusion partner: NS-1.
General Information
| Short Description | Mouse monoclonal anti-MUC3 for use in FC, IF and IHC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IF/IHC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | EBS-T-232 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | Flow Cytometry (0.5-1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (1-2 µg/ml). Immunohistology (formalin-fixed: 1-2 µg/ml for 30 min at RT; requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 followed by cooling at |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8°C upon receipt. |
Target Information
| Gene Symbol | MUC3A |
| Gene ID | 4584 |
| Uniprot ID | MUC3A_HUMAN |
| Immunogen | A BALB/c mouse was immunized with synthetic human MUC3 (SIB-35) peptide. Fusion partner: NS-1. |
Additional Info
| Post Translational Modifications | Highly O-glycosylated and probably also N-glycosylated. |
| Function | Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling. |
| Protein Name | Mucin-3aMuc-3aIntestinal Mucin-3a |
| Database Links | Reactome: R-HSA-5083625Reactome: R-HSA-5083632Reactome: R-HSA-5083636Reactome: R-HSA-5621480Reactome: R-HSA-913709Reactome: R-HSA-977068 |
| Cellular Localisation | Isoform 1: MembraneSingle-Pass Membrane ProteinIsoform 2: SecretedIsoform 3: SecretedIsoform 4: SecretedIsoform 5: Secreted |
| Alternative Antibody Names | Anti-Mucin-3a antibodyAnti-Muc-3a antibodyAnti-Intestinal Mucin-3a antibodyAnti-MUC3A antibodyAnti-MUC3 antibody |
Information sourced from Uniprot.org