| Host: | Mouse |
| Applications: | FC/IF/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-MUC3 is suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | EBS-T-232 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2ak |
| Formulation: | PBS with 0.02% Sodium Azide. |
| Purification: | Affinity purified from tissue culture. |
| Concentration: | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Dilution Range: | Flow Cytometry (0.5-1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (1-2 µg/ml). Immunohistology (formalin-fixed: 1-2 µg/ml for 30 min at RT; requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 followed by cooling at |
| Storage Instruction: | Store for up to 1 year at 2-8°C upon receipt. |
| Gene Symbol: | MUC3A |
| Gene ID: | 4584 |
| Uniprot ID: | MUC3A_HUMAN |
| Immunogen: | A BALB/c mouse was immunized with synthetic human MUC3 (SIB-35) peptide. Fusion partner: NS-1. |
| Post Translational Modifications | Highly O-glycosylated and probably also N-glycosylated. |
| Function | Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling. |
| Protein Name | Mucin-3aMuc-3aIntestinal Mucin-3a |
| Database Links | Reactome: R-HSA-5083625Reactome: R-HSA-5083632Reactome: R-HSA-5083636Reactome: R-HSA-5621480Reactome: R-HSA-913709Reactome: R-HSA-977068 |
| Cellular Localisation | Isoform 1: MembraneSingle-Pass Membrane ProteinIsoform 2: SecretedIsoform 3: SecretedIsoform 4: SecretedIsoform 5: Secreted |
| Alternative Antibody Names | Anti-Mucin-3a antibodyAnti-Muc-3a antibodyAnti-Intestinal Mucin-3a antibodyAnti-MUC3A antibodyAnti-MUC3 antibody |
Information sourced from Uniprot.org
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