Anti-MTMR8 antibody (430-560) (STJ119765)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MTMR8 (430-560) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTMR8 |
| Gene ID | 55613 |
| Uniprot ID | MTMR8_HUMAN |
| Immunogen Region | 430-560 |
| Immunogen Sequence | HVFSCQFGNFLGNCQKDRED LRVYEKTHSVWPFLVQRKPD FRNPLYKGFTMYGVLNPSTV PYNIQFWCGMYNRFDKGLQP KQSMLESLLEIKKQRAMLET DVHELEKKLKVRDEPPEEIC TCSQLGNILSQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 430-560 of human MTMR8 (NP_060147.2). |
Additional Info
| Function | Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, generating phosphatidylinositol and phosphatidylinositol 5-phosphate. In complex with MTMR9, negatively regulates autophagy. |
| Protein Name | Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr8Myotubularin-Related Protein 8Phosphatidylinositol-3-Phosphate Phosphatase |
| Database Links | Reactome: R-HSA-1660499 |
| Cellular Localisation | Nucleus Envelope |
| Alternative Antibody Names | Anti-Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr8 antibodyAnti-Myotubularin-Related Protein 8 antibodyAnti-Phosphatidylinositol-3-Phosphate Phosphatase antibodyAnti-MTMR8 antibody |
Information sourced from Uniprot.org