Host: |
Rabbit |
Applications: |
WB/IHC-P/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MTMR8 |
Gene ID: |
55613 |
Uniprot ID: |
MTMR8_HUMAN |
Immunogen Region: |
430-560 |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 430-560 of human MTMR8 (NP_060147.2). |
Immunogen Sequence: |
HVFSCQFGNFLGNCQKDRED LRVYEKTHSVWPFLVQRKPD FRNPLYKGFTMYGVLNPSTV PYNIQFWCGMYNRFDKGLQP KQSMLESLLEIKKQRAMLET DVHELEKKLKVRDEPPEEIC TCSQLGNILSQ |
Function | Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, generating phosphatidylinositol and phosphatidylinositol 5-phosphate. In complex with MTMR9, negatively regulates autophagy. |
Protein Name | Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr8Myotubularin-Related Protein 8Phosphatidylinositol-3-Phosphate Phosphatase |
Database Links | Reactome: R-HSA-1660499 |
Cellular Localisation | Nucleus Envelope |
Alternative Antibody Names | Anti-Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr8 antibodyAnti-Myotubularin-Related Protein 8 antibodyAnti-Phosphatidylinositol-3-Phosphate Phosphatase antibodyAnti-MTMR8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance