Anti-MTM1 antibody (C-Term) (STJ70068)

SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
STJ70068-100
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General Information

Short DescriptionGoat polyclonal antibody anti-MTM1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
ApplicationsPep-ELISA/WB/IHC
HostGoat
ReactivityHuman/Mouse/Dog/Cow
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration0.5 mg/mL
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution RangePeptide ELISA: antibody detection limit dilution 1:16000.
WB: Approx 70kDa band observed in lysates of Human and Mouse Skeletal Muscle and of cell line HepG2 (calculated MW of 69.9kDa according to NP_000243.1and 69.6kDa according to Mouse NP_0011
Formulation0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage InstructionStore at-20°C on receipt and minimise freeze-thaw cycles.

Target Information

Gene SymbolMTM1
Gene ID4534
Uniprot IDMTM1_HUMAN
Accession NumberNP_000243.1
Immunogen RegionC-Term
Immunogen SequenceSSPSQMMPHVQTHF

Additional Info

Protein Name Myotubularin
Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase
Phosphatidylinositol-3-Phosphate Phosphatase
Database Links Reactome: R-HSA-1660499
Reactome: R-HSA-1660516
Reactome: R-HSA-1660517
Cellular Localisation Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Cell Projection
Filopodium
Ruffle
Late Endosome
Myofibril
Sarcomere
Localizes As A Dense Cytoplasmic Network
Also Localizes To The Plasma Membrane
Including Plasma Membrane Extensions Such As Filopodia And Ruffles
Predominantly Located In The Cytoplasm Following Interaction With Mtmr12
Recruited To The Late Endosome Following Egf Stimulation
In Skeletal Muscles
Co-Localizes With Mtmr12 In The Sarcomere
Alternative Antibody Names Anti-Myotubularin antibody
Anti-Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase antibody
Anti-Phosphatidylinositol-3-Phosphate Phosphatase antibody
Anti-MTM1 antibody
Anti-CG2 antibody

Information sourced from Uniprot.org

Citations

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