Anti-MTHFD2 antibody (40-250) [S4901RM] (STJ11104901)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase-Mitochondrial Includes-Nad-Dependent Methylenetetrahydrofolate Dehydrogenase-Methenyltetrahydrofolate Cyclohydrolase (40-250) antibody for use in WB and ELISA in hu |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4901RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:2000-1:8000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTHFD2 |
| Gene ID | 10797 |
| Uniprot ID | MTDC_HUMAN |
| Immunogen Region | 40-250 |
| Immunogen Sequence | ISGRKLAQQIKQEVRQEVEE WVASGNKRPHLSVILVGENP ASHSYVLNKTRAAAVVGINS ETIMKPASISEEELLNLINK LNNDDNVDGLLVQLPLPEHI DERRICNAVSPDKDVDGFHV INVGRMCLDQYSMLPATPWG VWEIIKRTGIPTLGKNVVVA GRSKNVGMPIAMLLHTDGAH ERPGGDATVTISHRYTPKEQ LKKHTILADIV |
| Specificity | Recombinant funsion protein containing a sequence corresponding to amino acids 40-250 of human MTHFD2 (NP_006627.2). |
Additional Info
| Function | Although its dehydrogenase activity is NAD-specific, it can also utilize NADP at a reduced efficiency. |
| Protein Name | Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase - Mitochondrial Includes - Nad-Dependent Methylenetetrahydrofolate Dehydrogenase - Methenyltetrahydrofolate Cyclohydrolase |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase - Mitochondrial Includes - Nad-Dependent Methylenetetrahydrofolate Dehydrogenase - Methenyltetrahydrofolate Cyclohydrolase antibodyAnti-MTHFD2 antibodyAnti-NMDMC antibody |
Information sourced from Uniprot.org