| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Rat/Dog/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-MTHFD1L (535-538) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 110kDa band observed in Human Brain (Cerebellum) (calculated MW of 106kDa according to NP_056255.2). The same band is observed in lysates of cell line NIH3T3, Mouse Brain and Ra |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | MTHFD1L |
| Gene ID: | 25902 |
| Uniprot ID: | C1TM_HUMAN |
| Immunogen Region: | 535-538 |
| Accession Number: | NP_056255.2 |
| Immunogen Sequence: | DTNDRFLRKITIGQ |
| Function | May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism complementing thus the enzymatic activities of MTHFD2. |
| Protein Name | Monofunctional C1-Tetrahydrofolate Synthase - MitochondrialFormyltetrahydrofolate Synthetase |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Monofunctional C1-Tetrahydrofolate Synthase - Mitochondrial antibodyAnti-Formyltetrahydrofolate Synthetase antibodyAnti-MTHFD1L antibodyAnti-FTHFSDC1 antibody |
Information sourced from Uniprot.org