Anti-MTHFD1L antibody (535-538) (STJ72572)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-MTHFD1L (535-538) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 110kDa band observed in Human Brain (Cerebellum) (calculated MW of 106kDa according to NP_056255.2). The same band is observed in lysates of cell line NIH3T3, Mouse Brain and Ra |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | MTHFD1L |
| Gene ID | 25902 |
| Uniprot ID | C1TM_HUMAN |
| Accession Number | NP_056255.2 |
| Immunogen Region | 535-538 |
| Immunogen Sequence | DTNDRFLRKITIGQ |
Additional Info
| Function | May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism complementing thus the enzymatic activities of MTHFD2. |
| Protein Name | Monofunctional C1-Tetrahydrofolate Synthase - MitochondrialFormyltetrahydrofolate Synthetase |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Monofunctional C1-Tetrahydrofolate Synthase - Mitochondrial antibodyAnti-Formyltetrahydrofolate Synthetase antibodyAnti-MTHFD1L antibodyAnti-FTHFSDC1 antibody |
Information sourced from Uniprot.org