Anti-CXCR2 antibody (445-538) (STJ506203)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide corresponding to amino acids within region 445-538 on mouse C-X-C Chemokine Receptot type 2.
General Information
| Short Description | Rabbit polyclonal antibody anti-CXCR2 (445-538) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5-1.5 Mu g/Mu l |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500ELISA: 1:10, 000IP: 1:200 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Cxcr2 |
| Gene ID | 12765 |
| Uniprot ID | CXCR2_MOUSE |
| Immunogen | Synthetic peptide corresponding to amino acids within region 445-538 on mouse C-X-C Chemokine Receptot type 2. |
| Immunogen Region | 445-538 |
Additional Info
| Post Translational Modifications | Phosphorylated upon ligand binding.which is required for desensitization. |
| Function | Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. |
| Protein Name | C-X-C Chemokine Receptor Type 2Cxc-R2Cxcr-2Gro/Mgsa ReceptorHigh Affinity Interleukin-8 Receptor BIl-8r BCd Antigen Cd182 |
| Database Links | Reactome: R-MMU-380108Reactome: -MMU-418594Reactome: -MMU-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-X-C Chemokine Receptor Type 2 antibodyAnti-Cxc-R2 antibodyAnti-Cxcr-2 antibodyAnti-Gro/Mgsa Receptor antibodyAnti-High Affinity Interleukin-8 Receptor B antibodyAnti-Il-8r B antibodyAnti-Cd Antigen Cd182 antibodyAnti-Cxcr2 antibodyAnti-Cmkar2 antibodyAnti-Gpcr16 antibodyAnti-Il8rb antibody |
Information sourced from Uniprot.org