Anti-MTARC2 antibody (140-190 aa) (STJ198146)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human MOSC2 at the amino acid range 140-190
General Information
| Short Description | Rabbit polyclonal anti-Mitochondrial amidoxime reducing component 2 (140-190 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTARC2 |
| Gene ID | 54996 |
| Uniprot ID | MARC2_HUMAN |
| Immunogen | Synthesized peptide derived from the human MOSC2 at the amino acid range 140-190 |
| Immunogen Region | 140-190 aa |
| Specificity | This antibody detects endogenous levels of human MOSC2 |
Additional Info
| Function | Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles. As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability. May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis. Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction. |
| Protein Name | Mitochondrial Amidoxime Reducing Component 2Marc2Molybdenum Cofactor Sulfurase C-Terminal Domain-Containing Protein 2Mosc Domain-Containing Protein 2Moco Sulfurase C-Terminal Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Mitochondrion Outer MembranePeripheral Membrane ProteinPeroxisome |
| Alternative Antibody Names | Anti-Mitochondrial Amidoxime Reducing Component 2 antibodyAnti-Marc2 antibodyAnti-Molybdenum Cofactor Sulfurase C-Terminal Domain-Containing Protein 2 antibodyAnti-Mosc Domain-Containing Protein 2 antibodyAnti-Moco Sulfurase C-Terminal Domain-Containing Protein 2 antibodyAnti-MTARC2 antibodyAnti-MARC2 antibodyAnti-MOSC2 antibody |
Information sourced from Uniprot.org