| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Mitochondrial amidoxime reducing component 2 (140-190 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MTARC2 |
| Gene ID: |
54996 |
| Uniprot ID: |
MARC2_HUMAN |
| Immunogen Region: |
140-190 aa |
| Specificity: |
This antibody detects endogenous levels of human MOSC2 |
| Immunogen: |
Synthesized peptide derived from the human MOSC2 at the amino acid range 140-190 |
| Function | Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles. As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability. May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis. Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction. |
| Protein Name | Mitochondrial Amidoxime Reducing Component 2Marc2Molybdenum Cofactor Sulfurase C-Terminal Domain-Containing Protein 2Mosc Domain-Containing Protein 2Moco Sulfurase C-Terminal Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Mitochondrion Outer MembranePeripheral Membrane ProteinPeroxisome |
| Alternative Antibody Names | Anti-Mitochondrial Amidoxime Reducing Component 2 antibodyAnti-Marc2 antibodyAnti-Molybdenum Cofactor Sulfurase C-Terminal Domain-Containing Protein 2 antibodyAnti-Mosc Domain-Containing Protein 2 antibodyAnti-Moco Sulfurase C-Terminal Domain-Containing Protein 2 antibodyAnti-MTARC2 antibodyAnti-MARC2 antibodyAnti-MOSC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
