Anti-MTAP antibody (233-283) (STJ503533)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 233-283 on human methylthioadenosine phosphorylase protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-MTAP (233-283) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Monkey/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.55-0.75 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | MTAP |
| Gene ID | 4507 |
| Uniprot ID | MTAP_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 233-283 on human methylthioadenosine phosphorylase protein. |
| Immunogen Region | 233-283 |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Function | Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. |
| Protein Name | S-Methyl-5'-Thioadenosine Phosphorylase5'-Methylthioadenosine PhosphorylaseMta PhosphorylaseMtapMtapase |
| Database Links | Reactome: R-HSA-1237112Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-S-Methyl-5'-Thioadenosine Phosphorylase antibodyAnti-5'-Methylthioadenosine Phosphorylase antibodyAnti-Mta Phosphorylase antibodyAnti-Mtap antibodyAnti-Mtapase antibodyAnti-MTAP antibodyAnti-MSAP antibody |
Information sourced from Uniprot.org