Host: | Rabbit |
Applications: | ELISA/IP/WB |
Reactivity: | Human/Monkey/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-MTAP (233-283) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
Purification: | Affinity Purified |
Concentration: | 0.55-0.75 µg/µl |
Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | MTAP |
Gene ID: | 4507 |
Uniprot ID: | MTAP_HUMAN |
Immunogen Region: | 233-283 |
Immunogen: | Synthetic peptide taken within amino acid region 233-283 on human methylthioadenosine phosphorylase protein. |
Tissue Specificity | Ubiquitously expressed. |
Function | Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. |
Protein Name | S-Methyl-5'-Thioadenosine Phosphorylase5'-Methylthioadenosine PhosphorylaseMta PhosphorylaseMtapMtapase |
Database Links | Reactome: R-HSA-1237112Reactome: R-HSA-8950505 |
Cellular Localisation | CytoplasmNucleus |
Alternative Antibody Names | Anti-S-Methyl-5'-Thioadenosine Phosphorylase antibodyAnti-5'-Methylthioadenosine Phosphorylase antibodyAnti-Mta Phosphorylase antibodyAnti-Mtap antibodyAnti-Mtapase antibodyAnti-MTAP antibodyAnti-MSAP antibody |
Information sourced from Uniprot.org