Anti-MSRB2 antibody (10-182) (STJ110662)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MSRB2 (10-182) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MSRB2 |
| Gene ID | 22921 |
| Uniprot ID | MSRB2_HUMAN |
| Immunogen Region | 10-182 |
| Immunogen Sequence | GLTLGTAPRRAVRGQAGGGG PGTGPGLGEAGSLATCELPL AKSEWQKKLTPEQFYVTREK GTEPPFSGIYLNNKEAGMYH CVCCDSPLFSSEKKYCSGTG WPSFSEAHGTSGSDESHTGI LRRLDTSLGSARTEVVCKQC EAHLGHVFPDGPGPNGQRFC INSVALKFKPRKH |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 10-182 of human MSRB2 (NP_036360.3). |
Additional Info
| Tissue Specificity | Ubiquitous. Detected in retina, ocular ciliary body, skeletal muscle, heart, colon, bone marrow, cerebellum, small intestine, fetal brain, fetal liver, kidney, spinal cord, lung, placenta and prostate. |
| Function | Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. |
| Protein Name | Methionine-R-Sulfoxide Reductase B2 - MitochondrialMsrb2 |
| Database Links | Reactome: R-HSA-5676934 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Methionine-R-Sulfoxide Reductase B2 - Mitochondrial antibodyAnti-Msrb2 antibodyAnti-MSRB2 antibodyAnti-CBS-1 antibodyAnti-MSRB antibodyAnti-CGI-131 antibody |
Information sourced from Uniprot.org