• Western blot analysis of extracts of various cell lines, using MSRB2 antibody (STJ110662) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
  • Immunohistochemistry analysis of paraffin-embedded human lung cancer using MSRB2 Rabbit polyclonal antibody (STJ110662) at dilution of 1:200 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry of paraffin-embedded human lung cancer using MSRB2 rabbit polyclonal antibody (STJ110662) at dilution of 1:200 (40x lens).
  • Western blot analysis of extracts of various cell lines, using MSRB2 antibody (STJ110662) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-MSRB2 antibody (10-182) (STJ110662)

SKU:
STJ110662

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MSRB2 (10-182) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MSRB2
Gene ID: 22921
Uniprot ID: MSRB2_HUMAN
Immunogen Region: 10-182
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 10-182 of human MSRB2 (NP_036360.3).
Immunogen Sequence: GLTLGTAPRRAVRGQAGGGG PGTGPGLGEAGSLATCELPL AKSEWQKKLTPEQFYVTREK GTEPPFSGIYLNNKEAGMYH CVCCDSPLFSSEKKYCSGTG WPSFSEAHGTSGSDESHTGI LRRLDTSLGSARTEVVCKQC EAHLGHVFPDGPGPNGQRFC INSVALKFKPRKH
Tissue Specificity Ubiquitous. Detected in retina, ocular ciliary body, skeletal muscle, heart, colon, bone marrow, cerebellum, small intestine, fetal brain, fetal liver, kidney, spinal cord, lung, placenta and prostate.
Function Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance.
Protein Name Methionine-R-Sulfoxide Reductase B2 - Mitochondrial
Msrb2
Database Links Reactome: R-HSA-5676934
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-Methionine-R-Sulfoxide Reductase B2 - Mitochondrial antibody
Anti-Msrb2 antibody
Anti-MSRB2 antibody
Anti-CBS-1 antibody
Anti-MSRB antibody
Anti-CGI-131 antibody

Information sourced from Uniprot.org

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