Anti-MSRB1 antibody (STJA0007869)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SEPX1
General Information
| Short Description | Rabbit polyclonal anti-Methionine-R-sulfoxide reductase B1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MSRB1 |
| Gene ID | 51734 |
| Uniprot ID | MSRB1_HUMAN |
| Immunogen | Synthesized peptide derived from human SEPX1 |
| Specificity | This antibody detects endogenous levels of SEPX1 at Human, Mouse, Rat |
Additional Info
| Function | Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages. |
| Protein Name | Methionine-R-Sulfoxide Reductase B1Msrb1Selenoprotein XSelx |
| Database Links | Reactome: R-HSA-5676934 |
| Cellular Localisation | CytoplasmNucleusCytoskeleton |
| Alternative Antibody Names | Anti-Methionine-R-Sulfoxide Reductase B1 antibodyAnti-Msrb1 antibodyAnti-Selenoprotein X antibodyAnti-Selx antibodyAnti-MSRB1 antibodyAnti-SEPX1 antibodyAnti-HSPC270 antibody |
Information sourced from Uniprot.org