| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Methionine-R-sulfoxide reductase B1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MSRB1 |
| Gene ID: |
51734 |
| Uniprot ID: |
MSRB1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of SEPX1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human SEPX1 |
| Function | Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages. |
| Protein Name | Methionine-R-Sulfoxide Reductase B1Msrb1Selenoprotein XSelx |
| Database Links | Reactome: R-HSA-5676934 |
| Cellular Localisation | CytoplasmNucleusCytoskeleton |
| Alternative Antibody Names | Anti-Methionine-R-Sulfoxide Reductase B1 antibodyAnti-Msrb1 antibodyAnti-Selenoprotein X antibodyAnti-Selx antibodyAnti-MSRB1 antibodyAnti-SEPX1 antibodyAnti-HSPC270 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
