• Western blot analysis of lysates from HUVEC cells, using MSH3 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using MSH3 Polyclonal Antibody diluted at 1：2000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-MSH3 antibody (51-100) (STJ94262)

SKU:
STJ94262

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DNA mismatch repair protein Msh3 (51-100) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MSH3
Gene ID: 4437
Uniprot ID: MSH3_HUMAN
Immunogen Region: 51-100
Specificity: MSH3 Polyclonal Antibody detects endogenous levels of MSH3 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human MSH3. AA range:51-100
Function Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
Protein Name Dna Mismatch Repair Protein Msh3
Hmsh3
Divergent Upstream Protein
Dup
Mismatch Repair Protein 1
Mrp1
Database Links Reactome: R-HSA-5358606
Reactome: R-HSA-5632927
Reactome: R-HSA-5632928
Alternative Antibody Names Anti-Dna Mismatch Repair Protein Msh3 antibody
Anti-Hmsh3 antibody
Anti-Divergent Upstream Protein antibody
Anti-Dup antibody
Anti-Mismatch Repair Protein 1 antibody
Anti-Mrp1 antibody
Anti-MSH3 antibody
Anti-DUC1 antibody
Anti-DUG antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance