Anti-MPP2 antibody (439-489 aa) (STJ196063)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human MPP2 at the amino acid range 439-489
General Information
| Short Description | Rabbit polyclonal anti-MAGUK p55 subfamily member 2 (439-489 aa) for use in WB and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MPP2 |
| Gene ID | 4355 |
| Uniprot ID | MPP2_HUMAN |
| Immunogen | Synthesized peptide derived from the human MPP2 at the amino acid range 439-489 |
| Immunogen Region | 439-489 aa |
| Specificity | This antibody detects endogenous levels of MPP2 at Human/Mouse |
Additional Info
| Function | Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density. In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression. Seems to negatively regulate SRC function in epithelial cells. |
| Protein Name | Maguk P55 Subfamily Member 2Discs Large Homolog 2Protein Mpp2 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonMembraneCell ProjectionDendritePostsynaptic DensityProminently Expressed In The Postsynaptic Densities Of Dendritic SpinesIs Also Detected In Dendritic Shafts |
| Alternative Antibody Names | Anti-Maguk P55 Subfamily Member 2 antibodyAnti-Discs Large Homolog 2 antibodyAnti-Protein Mpp2 antibodyAnti-MPP2 antibodyAnti-DLG2 antibody |
Information sourced from Uniprot.org