| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-MAGUK p55 subfamily member 2 (439-489 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MPP2 |
| Gene ID: | 4355 |
| Uniprot ID: | MPP2_HUMAN |
| Immunogen Region: | 439-489 aa |
| Specificity: | This antibody detects endogenous levels of MPP2 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human MPP2 at the amino acid range 439-489 |
| Function | Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density. In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression. Seems to negatively regulate SRC function in epithelial cells. |
| Protein Name | Maguk P55 Subfamily Member 2Discs Large Homolog 2Protein Mpp2 |
| Cellular Localisation | CytoplasmCytoskeletonMembraneCell ProjectionDendritePostsynaptic DensityProminently Expressed In The Postsynaptic Densities Of Dendritic SpinesIs Also Detected In Dendritic Shafts |
| Alternative Antibody Names | Anti-Maguk P55 Subfamily Member 2 antibodyAnti-Discs Large Homolog 2 antibodyAnti-Protein Mpp2 antibodyAnti-MPP2 antibodyAnti-DLG2 antibody |
Information sourced from Uniprot.org