| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MPP1 (1-270) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MPP1 |
| Gene ID: |
4354 |
| Uniprot ID: |
EM55_HUMAN |
| Immunogen Region: |
1-270 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MPP1 (NP_002427.1). |
| Immunogen Sequence: |
MTLKASEGESGGSMHTALSD LYLEHLLQKRSRPEAVSHPL NTVTEDMYTNGSPAPGSPAQ VKGQEVRKVRLIQFEKVTEE PMGITLKLNEKQSCTVARIL HGGMIHRQGSLHVGDEILEI NGTNVTNHSVDQLQKAMKET KGMISLKVIPNQQSRLPALQ MFMRAQFDYDPKKDNLIPCK EAGLKFATGDIIQIINKDDS NWWQGRVEGSSKESAGLIPS PELQEWRVASMAQSAPSEA |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Palmitoylated. |
| Function | Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity. |
| Protein Name | 55 Kda Erythrocyte Membrane ProteinP55Membrane Protein - Palmitoylated 1 |
| Database Links | Reactome: R-HSA-9662361 |
| Cellular Localisation | Cell MembraneLipid-AnchorCell ProjectionStereociliumColocalizes With Whrn At Stereocilium Tip During Hair Cell DevelopmentColocalizes With Pals1 In The RetinaAt The Outer Limiting Membrane (Olm)Colocalizes With Whrn In The RetinaOuter Plexifirm Layer (Opl)Basal Bodies And At The Connecting Cilium (Cc)Colocalizes With Nf2 In Non-Myelin-Forming Schwann Cells |
| Alternative Antibody Names | Anti-55 Kda Erythrocyte Membrane Protein antibodyAnti-P55 antibodyAnti-Membrane Protein - Palmitoylated 1 antibodyAnti-MPP1 antibodyAnti-DXS552E antibodyAnti-EMP55 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
