Anti-MPP1 antibody (1-270) (STJ28220)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MPP1 (1-270) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MPP1 |
| Gene ID | 4354 |
| Uniprot ID | EM55_HUMAN |
| Immunogen Region | 1-270 |
| Immunogen Sequence | MTLKASEGESGGSMHTALSD LYLEHLLQKRSRPEAVSHPL NTVTEDMYTNGSPAPGSPAQ VKGQEVRKVRLIQFEKVTEE PMGITLKLNEKQSCTVARIL HGGMIHRQGSLHVGDEILEI NGTNVTNHSVDQLQKAMKET KGMISLKVIPNQQSRLPALQ MFMRAQFDYDPKKDNLIPCK EAGLKFATGDIIQIINKDDS NWWQGRVEGSSKESAGLIPS PELQEWRVASMAQSAPSEA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MPP1 (NP_002427.1). |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Palmitoylated. |
| Function | Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity. |
| Protein Name | 55 Kda Erythrocyte Membrane ProteinP55Membrane Protein - Palmitoylated 1 |
| Database Links | Reactome: R-HSA-9662361 |
| Cellular Localisation | Cell MembraneLipid-AnchorCell ProjectionStereociliumColocalizes With Whrn At Stereocilium Tip During Hair Cell DevelopmentColocalizes With Pals1 In The RetinaAt The Outer Limiting Membrane (Olm)Colocalizes With Whrn In The RetinaOuter Plexifirm Layer (Opl)Basal Bodies And At The Connecting Cilium (Cc)Colocalizes With Nf2 In Non-Myelin-Forming Schwann Cells |
| Alternative Antibody Names | Anti-55 Kda Erythrocyte Membrane Protein antibodyAnti-P55 antibodyAnti-Membrane Protein - Palmitoylated 1 antibodyAnti-MPP1 antibodyAnti-DXS552E antibodyAnti-EMP55 antibody |
Information sourced from Uniprot.org