• Western blot analysis of extracts from Jurkat cells, using MPP10 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-MPHOSPH10 antibody (60-140 aa) (STJ96444)

SKU:
STJ96444

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-U3 small nucleolar ribonucleoprotein protein MPP10 (60-140 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MPHOSPH10
Gene ID: 10199
Uniprot ID: MPP10_HUMAN
Immunogen Region: 60-140 aa
Specificity: MPP10 Polyclonal Antibody detects endogenous levels of MPP10 protein.
Immunogen: Synthesized peptide derived from MPP10 at the amino acid range 60-140
Function Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Protein Name U3 Small Nucleolar Ribonucleoprotein Protein Mpp10
M Phase Phosphoprotein 10
Database Links Reactome: R-HSA-6790901
Reactome: R-HSA-6791226
Cellular Localisation Nucleus
Nucleolus
Chromosome
Fibrillar Region Of The Nucleolus
After Dissolution Of The Nucleolus In Early M Phase Becomes Associated With Chromosomes Through Metaphase And Anaphase
In Telophase Localized To Small Cellular Prenucleolar Bodies That Not Always Contain Fibrillarin
The Reassociation With Nucleolus Is Preceeded By The Arrival Of Fibrillarin
Alternative Antibody Names Anti-U3 Small Nucleolar Ribonucleoprotein Protein Mpp10 antibody
Anti-M Phase Phosphoprotein 10 antibody
Anti-MPHOSPH10 antibody
Anti-MPP10 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance