Anti-MOGAT2 antibody (Internal) (STJ72346)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-MOGAT2 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Dog/Cow/Pig |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 37kDa band observed in Human Colon, Duodenum and Ileum lysates (calculated MW of 38.2kDa according to NP_079374.2). Recommended concentration: 0.05-0.2µg/ml. Primary incubation |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | MOGAT2 |
| Gene ID | 80168 |
| Uniprot ID | MOGT2_HUMAN |
| Accession Number | NP_079374.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | KESAAHILNRK |
Additional Info
| Function | Involved in glycerolipid synthesis and lipid metabolism. Catalyzes the formation of diacylglycerol, the precursor of triacylglycerol, by transferring the acyl chain of a fatty acyl-CoA to a monoacylglycerol. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0 at sn-2. Able to use 1-monoalkylglycerol (1-MAkG, 1-O-alkylglycerol) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG, 1-O-alkyl-3-acylglycerol or 1-O-alkyl-2-acylglycerol) and subsequently, with lower efficiency, may add another acyl chain producing monoalkyl-diacylglycerol (MADAG, 1-O-alkyl-2,3-diacylglycerol). Possesses weak but significant activity with diacylglycerol as substrate, producing triacylglycerol (triacyl-sn-glycerol). |
| Protein Name | 2-Acylglycerol O-Acyltransferase 2Acyl-Coa -Monoacylglycerol Acyltransferase 2Mgat2Hmgat2Diacylglycerol O-Acyltransferase Candidate 5Hdc5Diacylglycerol Acyltransferase 2-Like Protein 5Monoacylglycerol O-Acyltransferase 2 |
| Database Links | Reactome: R-HSA-75109 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinCytoplasmPerinuclear Region |
| Alternative Antibody Names | Anti-2-Acylglycerol O-Acyltransferase 2 antibodyAnti-Acyl-Coa -Monoacylglycerol Acyltransferase 2 antibodyAnti-Mgat2 antibodyAnti-Hmgat2 antibodyAnti-Diacylglycerol O-Acyltransferase Candidate 5 antibodyAnti-Hdc5 antibodyAnti-Diacylglycerol Acyltransferase 2-Like Protein 5 antibodyAnti-Monoacylglycerol O-Acyltransferase 2 antibodyAnti-MOGAT2 antibodyAnti-DC5 antibodyAnti-DGAT2L5 antibody |
Information sourced from Uniprot.org