Confocal imaging of frozen sections of paraffin-embedded Mouse brain using Myelin oligodendrocyte glycoprotein Rabbit monoclonal antibody (STJ11101981, dilution 1:100) followed by incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (dilution 1:500) (Red). DAPI was used for nuclear staining (Blue). Objective: 40x. Perform high pressure antigen retrieval with 0. 01M citrate buffer (pH 6. 0) prior to IF staining.

Anti-MOG antibody (1-100) [S1MR] (STJ11101981)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ11101981
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General Information

Short DescriptionRabbit monoclonal Myelin oligodendrocyte glycoprotein (1-100) antibody for use in WB, IF, ICC and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IF/ICC/ELISA
HostRabbit
ReactivityMouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDS1MR
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:1000-1:6000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolMOG
Gene ID4340
Uniprot IDMOG_HUMAN
Immunogen Region1-100
Immunogen SequenceMASLSRPSLPSCLCSFLLLL LLQVSSSYAGQFRVIGPRHP IRALVGDEVELPCRISPGKN ATGMEVGWYRPPFSRVVHLY RNGKDQDGDQAPEYRGRTEL
SpecificityA synthetic peptide corresponding to a sequence within amino acids 1-100 of human Myelin oligodendrocyte glycoprotein (NP_996532.2).

Additional Info

Tissue Specificity Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes.
Function Mediates homophilic cell-cell adhesion. Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. (Microbial infection) Acts as a receptor for rubella virus.
Protein Name Myelin-Oligodendrocyte Glycoprotein
Database Links
Cellular Localisation Isoform 1: Cell Membrane
Multi-Pass Membrane Protein
Isoform 5: Cell Membrane
Isoform 2: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 3: Cell Membrane
Isoform 4: Cell Membrane
Isoform 6: Cell Membrane
Isoform 7: Cell Membrane
Isoform 8: Cell Membrane
Isoform 9: Cell Membrane
Alternative Antibody Names Anti-Myelin-Oligodendrocyte Glycoprotein antibody
Anti-MOG antibody

Information sourced from Uniprot.org

Citations

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