Host: | Mouse |
Applications: | WB/IHC/IF/FC/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-Matrix metalloproteinase-9 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry and ELISA research applications. |
Clonality : | Monoclonal |
Clone ID : | 5G3 |
Conjugation: | Unconjugated |
Isotype: | IgG2a |
Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IHC 1:200-1:1000 IF 1:200-1:1000 FC 1:200-1:400 ELISA 1:10000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MMP9 |
Gene ID: | 4318 |
Uniprot ID: | MMP9_HUMAN |
Specificity: | MMP-9 Monoclonal Antibody detects endogenous levels of MMP-9 protein. |
Immunogen: | Purified recombinant fragment of human MMP-9 expressed in E. Coli. |
Post Translational Modifications | Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9. N- and O-glycosylated. |
Function | Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. |
Protein Name | Matrix Metalloproteinase-9 Mmp-9 92 Kda Gelatinase 92 Kda Type Iv Collagenase Gelatinase B Gelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 |
Database Links | Reactome: R-HSA-1433557 Reactome: R-HSA-1442490 Reactome: R-HSA-1474228 Reactome: R-HSA-1592389 Reactome: R-HSA-2022090 Reactome: R-HSA-3928665 Reactome: R-HSA-6785807 Reactome: R-HSA-6798695 Reactome: R-HSA-9009391 |
Cellular Localisation | Secreted Extracellular Space Extracellular Matrix |
Alternative Antibody Names | Anti-Matrix Metalloproteinase-9 antibody Anti-Mmp-9 antibody Anti-92 Kda Gelatinase antibody Anti-92 Kda Type Iv Collagenase antibody Anti-Gelatinase B antibody Anti-Gelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 antibody Anti-MMP9 antibody Anti-CLG4B antibody |
Information sourced from Uniprot.org