Anti-MMP8 antibody (101-467) (STJ24616)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MMP8 (101-467) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MMP8 |
| Gene ID | 4317 |
| Uniprot ID | MMP8_HUMAN |
| Immunogen Region | 101-467 |
| Immunogen Sequence | LTPGNPKWERTNLTYRIRNY TPQLSEAEVERAIKDAFELW SVASPLIFTRISQGEADINI AFYQRDHGDNSPFDGPNGIL AHAFQPGQGIGGDAHFDAEE TWTNTSANYNLFLVAAHEFG HSLGLAHSSDPGALMYPNYA FRETSNYSLPQDDIDGIQAI YGLSSNPIQPTGPSTPKPCD PSLTFDAITTLRGEILFFKD RYFWRRHPQLQRVEMNFISL FWPSLPTGIQAAYEDFDRD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 101-467 of human MMP8 (NP_002415.1). |
Additional Info
| Tissue Specificity | Neutrophils. |
| Function | Can degrade fibrillar type I, II, and III collagens. |
| Protein Name | Neutrophil CollagenaseMatrix Metalloproteinase-8Mmp-8Pmnl CollagenasePmnl-Cl |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasmic GranuleSecretedExtracellular SpaceExtracellular MatrixStored In Intracellular Granules |
| Alternative Antibody Names | Anti-Neutrophil Collagenase antibodyAnti-Matrix Metalloproteinase-8 antibodyAnti-Mmp-8 antibodyAnti-Pmnl Collagenase antibodyAnti-Pmnl-Cl antibodyAnti-MMP8 antibodyAnti-CLG1 antibody |
Information sourced from Uniprot.org