Anti-MMP8 antibody (101-467) (STJ24616)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ24616
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General Information

Short DescriptionRabbit polyclonal MMP8 (101-467) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:1000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolMMP8
Gene ID4317
Uniprot IDMMP8_HUMAN
Immunogen Region101-467
Immunogen SequenceLTPGNPKWERTNLTYRIRNY TPQLSEAEVERAIKDAFELW SVASPLIFTRISQGEADINI AFYQRDHGDNSPFDGPNGIL AHAFQPGQGIGGDAHFDAEE TWTNTSANYNLFLVAAHEFG HSLGLAHSSDPGALMYPNYA FRETSNYSLPQDDIDGIQAI YGLSSNPIQPTGPSTPKPCD PSLTFDAITTLRGEILFFKD RYFWRRHPQLQRVEMNFISL FWPSLPTGIQAAYEDFDRD
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 101-467 of human MMP8 (NP_002415.1).

Additional Info

Tissue Specificity Neutrophils.
Function Can degrade fibrillar type I, II, and III collagens.
Protein Name Neutrophil Collagenase
Matrix Metalloproteinase-8
Mmp-8
Pmnl Collagenase
Pmnl-Cl
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1474228
Reactome: R-HSA-1592389
Reactome: R-HSA-6798695
Cellular Localisation Cytoplasmic Granule
Secreted
Extracellular Space
Extracellular Matrix
Stored In Intracellular Granules
Alternative Antibody Names Anti-Neutrophil Collagenase antibody
Anti-Matrix Metalloproteinase-8 antibody
Anti-Mmp-8 antibody
Anti-Pmnl Collagenase antibody
Anti-Pmnl-Cl antibody
Anti-MMP8 antibody
Anti-CLG1 antibody

Information sourced from Uniprot.org

Citations

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