| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MMP8 |
| Gene ID: | 4317 |
| Uniprot ID: | MMP8_HUMAN |
| Immunogen Region: | 101-467 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 101-467 of human MMP8 (NP_002415.1). |
| Immunogen Sequence: | LTPGNPKWERTNLTYRIRNY TPQLSEAEVERAIKDAFELW SVASPLIFTRISQGEADINI AFYQRDHGDNSPFDGPNGIL AHAFQPGQGIGGDAHFDAEE TWTNTSANYNLFLVAAHEFG HSLGLAHSSDPGALMYPNYA FRETSNYSLPQDDIDGIQAI YGLSSNPIQPTGPSTPKPCD PSLTFDAITTLRGEILFFKD RYFWRRHPQLQRVEMNFISL FWPSLPTGIQAAYEDFDRD |
| Tissue Specificity | Neutrophils. |
| Function | Can degrade fibrillar type I, II, and III collagens. |
| Protein Name | Neutrophil Collagenase Matrix Metalloproteinase-8 Mmp-8 Pmnl Collagenase Pmnl-Cl |
| Database Links | Reactome: R-HSA-1442490 Reactome: R-HSA-1474228 Reactome: R-HSA-1592389 Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasmic Granule Secreted Extracellular Space Extracellular Matrix Stored In Intracellular Granules |
| Alternative Antibody Names | Anti-Neutrophil Collagenase antibody Anti-Matrix Metalloproteinase-8 antibody Anti-Mmp-8 antibody Anti-Pmnl Collagenase antibody Anti-Pmnl-Cl antibody Anti-MMP8 antibody Anti-CLG1 antibody |
Information sourced from Uniprot.org