Anti-MMP25 antibody (321-539) (STJ118331)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MMP25 (321-539) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MMP25 |
| Gene ID | 64386 |
| Uniprot ID | MMP25_HUMAN |
| Immunogen Region | 321-539 |
| Immunogen Sequence | FDAIANIRGETFFFKGPWFW RLQPSGQLVSPRPARLHRFW EGLPAQVRVVQAAYARHRDG RILLFSGPQFWVFQDRQLEG GARPLTELGLPPGEEVDAVF SWPQNGKTYLVRGRQYWRYD EAAARPDPGYPRDLSLWEGA PPSPDDVTVSNAGDTYFFKG AHYWRFPKNSIKTEPDAPQP MGPNWLDCPAPSSGPRAPRP PKATPVSETCDCQCELNQA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 321-539 of human MMP25 (NP_071913.1). |
Additional Info
| Tissue Specificity | Expressed predominantly in leukocytes, lung and spleen. Expressed also in colon carcinoma, astrocytoma and glioblastomas. |
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | May activate progelatinase A. |
| Protein Name | Matrix Metalloproteinase-25Mmp-25LeukolysinMembrane-Type Matrix Metalloproteinase 6Mt-Mmp 6Mtmmp6Membrane-Type-6 Matrix MetalloproteinaseMt6-MmpMt6mmp |
| Database Links | Reactome: R-HSA-1592389Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorExtracellular SideSecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Matrix Metalloproteinase-25 antibodyAnti-Mmp-25 antibodyAnti-Leukolysin antibodyAnti-Membrane-Type Matrix Metalloproteinase 6 antibodyAnti-Mt-Mmp 6 antibodyAnti-Mtmmp6 antibodyAnti-Membrane-Type-6 Matrix Metalloproteinase antibodyAnti-Mt6-Mmp antibodyAnti-Mt6mmp antibodyAnti-MMP25 antibodyAnti-MMP20 antibodyAnti-MMPL1 antibodyAnti-MT6MMP antibody |
Information sourced from Uniprot.org