| Short Description : | Rabbit polyclonal MMP11 (239-488) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MMP11 |
| Gene ID: | 4320 |
| Uniprot ID: | MMP11_HUMAN |
| Immunogen Region: | 239-488 |
| Immunogen Sequence: | FRYPLSLSPDDCRGVQHLYG QPWPTVTSRTPALGPQAGID TNEIAPLEPDAPPDACEASF DAVSTIRGELFFFKAGFVWR LRGGQLQPGYPALASRHWQG LPSPVDAAFEDAQGHIWFFQ GAQYWVYDGEKPVLGPAPLT ELGLVRFPVHAALVWGPEKN KIYFFRGRDYWRFHPSTRRV DSPVPRRATDWRGVPSEIDA AFQDADGYAYFLRGRLYWKF DPVKVKALEGFPRLVGPDF |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 239-488 of human MMP11 (NP_005931.2). |
| Tissue Specificity | Specifically expressed in stromal cells of breast carcinomas. |
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | May play an important role in the progression of epithelial malignancies. |
| Protein Name | Stromelysin-3Sl-3St3Matrix Metalloproteinase-11Mmp-11 |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Stromelysin-3 antibodyAnti-Sl-3 antibodyAnti-St3 antibodyAnti-Matrix Metalloproteinase-11 antibodyAnti-Mmp-11 antibodyAnti-MMP11 antibodyAnti-STMY3 antibody |
Information sourced from Uniprot.org
